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Clinical Research Services

Pricing and service scope

Every project starts with a free feasibility assessment. If the data cannot support a high-quality publication, we explain this and stop without charging. A formal quotation follows the assessment; any surcharges are itemised before the contract is signed.

Request an assessmentThree package tiers

Free feasibility assessment · Quotation after assessment · We do not promise publication outcomes

01 Clinical Research

Three package tiers

All target timelines start when the complete data are available. A formal quotation follows the free assessment.

Collaboration starter

from ¥12,800

For existing data requiring methodological support

  • Statistical analysis (core models including propensity score matching (PSM), Cox and meta-analysis)
  • Basic data cleaning
  • Standard figures and tables
  • Analysis code and key decision records
  • Monthly email reports
  • Contractual target timeline: 4–8 weeks from receipt of complete data

Excludes study design, full-manuscript language editing and guidance on reviewer responses. Full-manuscript language editing and reviewer response guidance are available as optional services (see below); study design can be commissioned separately, priced per project.

Book a methodology assessment

Full-service management

from ¥25,800

For the full process: design + data + writing

  • Study design (Population, Intervention, Comparator and Outcome (PICO) + sample size)
  • Advanced data cleaning + multiple imputation by chained equations (MICE)
  • Statistical analysis (including sensitivity analyses)
  • Publication-quality figure redrawing (ggplot2, TIFF / vector PDF)
  • Full manuscript editing
  • Up to 3 in-scope revisions (scope in the next section)
  • Analysis code and key decision records
  • Weekly reports every Friday
  • Contractual target timeline: 12–16 weeks from receipt of complete data
Book a methodology assessment

Multicentre / RCT

Custom pricing

For the design and full process of multicentre studies or randomised controlled trials

  • Case report form (CRF) design + database development + data dictionary
  • Managing multicentre data heterogeneity
  • Independent statistician review
  • Up to 3 in-scope revisions
  • Weekly reports + monthly risk reviews
  • Contractual target timeline: 6–12 months from receipt of complete data
Book a methodology assessment
For pharmaceutical projects, see Medical Writing

02 Clinical Research

Full comparison

Full comparison of Collaboration starter and Full-service management
Service scopeCollaboration starter from ¥12,800Full-service management from ¥25,800
Free feasibility assessment✓ Included✓ Included
Study design (PICO + sample size)— Commission separately, priced per project✓ Included
Data cleaningBasic cleaningAdvanced cleaning + MICE multiple imputation
Statistical analysis✓ Core models including PSM / Cox / meta-analysis✓ Includes sensitivity analyses
Publication-quality figure redrawing (ggplot2)— Optional service✓ TIFF / vector PDF
Full manuscript editing— Optional service✓ Included
Reviewer response guidance— Optional service✓ Up to 3 in-scope revisions
Weekly progress reportsMonthly email reportsWeekly reports every Friday
Analysis code + key decision records✓ Included✓ Included
Independent recalculation by quality control (a second person reruns the primary analysis)— Lead self-check before delivery✓ Included
Independent statistician review— Optional service— Optional service (included in Multicentre / RCT)
InvoicesStandard VAT invoice / special VAT invoice (增值税专用发票)Standard VAT invoice / special VAT invoice (增值税专用发票)
PaymentSingle payment / two instalmentsSingle payment / two instalments (50% on signing + 50% before submission)
Contractual target timeline4–8 weeks12–16 weeks
Refund Policy Clause 2 applies—✓ Applies if unresolved after 3 revisions or appeals

Multicentre / RCT includes everything in Full-service management, with pricing agreed according to project scale.

Clients can upgrade from Collaboration starter to Full-service management by paying the difference; all fees already paid are credited in full.

03 Clinical Research

Optional services

Optional services and starting prices
ServicesStarting priceSuitable for
Single statistical analysisfrom ¥6,800Cleaned data requiring a single model such as PSM / Cox / meta-analysis
Single figure redrawing¥800–¥1,500 / figureExisting results requiring publication-quality ggplot2 vector figures
Standalone reviewer response guidancefrom ¥3,800 / roundReceived reviewer comments requiring structured responses
Standalone Methods revisionfrom ¥2,800 / manuscriptMethods section standardisation + Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) / Consolidated Standards of Reporting Trials (CONSORT) self-check
Full manuscript editing and submission packagefrom ¥6,800 / manuscriptComplete manuscript + cover letter + submission system guidance
Independent statistician reviewfrom ¥6,800 / projectAnalysis completed externally, requiring an independent rerun by a second statistician
Multicentre database designfrom ¥18,800CRF design + database development + data dictionary

All prices are starting prices. Final fees reflect the workload assessed during the free assessment and are itemised in the quotation.

04 Clinical Research

Pricing factors

Formal quotations depend on study type, data complexity, depth of analysis and visualisation, and communication and management requirements.

Study types
Retrospective cohorts, prospective cohorts, multicentre studies and RCTs differ in workload and risk control requirements. Multicentre and prospective projects involve substantially more work than retrospective studies.
Data complexity
Missingness, number of variables, follow-up duration, consistency across centres, and the need for MICE imputation and multiple sensitivity analyses. Base scope: ≤30 variables + ≤2,000 participants.
Depth of analysis and visualisation
Basic regression, propensity score causal inference, time-dependent models / restricted cubic splines (RCS) / subgroups and interactions, and redrawing figures to journal publication standards.
Communication and management requirements
Whether regular weekly meetings, milestone acceptance, cross-team collaboration, and project management and risk alerts during submission are required.

05 Clinical Research

Fees and service boundaries

Starting-price scope
¥12,800 covers standard modelling with ≤30 variables and ≤2,000 participants. Additional work is priced in workload tiers, with surcharges itemised in the quotation before signing; no further charges are added after signing.
Invoices and payment
Standard VAT invoices and special VAT invoices (增值税专用发票) are issued at agreed milestones after the collaboration agreement is signed. Collaboration starter and Full-service management support a single payment or two instalments (50% on signing + 50% before submission); Multicentre / RCT uses milestone payments.
Free assessment
Every project starts with a free feasibility assessment. If the data cannot support a high-quality publication, we explain this and end the engagement without charging any fees.
Early termination
Clients may request termination in writing at any time. Settlement follows the service contract's Delivery Milestone Schedule: delivered and accepted milestones are charged at the contractual amount; unstarted milestones are refunded in full; milestones in progress are settled according to the completion percentage agreed in writing by both parties. The balance is refunded via the original payment method within 5 business days. This policy applies from 22 September 2026; contracts signed earlier remain subject to the version effective when signed ( Refund Policy Clause 3).

Two ways of working together, chosen when the contract is signed

Model 1 · Statistical co-authorship

Manuscript drafting
Our statistical experts analyse the data and prepare the first draft; researchers review, revise and give final approval
Submission and revision
Researchers submit the manuscript and approve each revised version
Disclosure
Authorship under our company's real affiliation; truthful contribution and conflict of interest statements
Eligibility
Available for some projects, assessed before signing; not applicable to degree theses

Model 2 · Guided self-writing

Manuscript drafting
Researchers write the full manuscript; we provide statistical analysis and written comments
Submission and revision
Researchers submit and respond to reviewers; we provide guidance on revision approaches
Disclosure
No authorship; contribution stated in the acknowledgements
Eligibility
All projects

Resident physicians in standardised training and graduate students who choose statistical co-authorship need written consent from their supervisor and their institution. Please check in advance with your institution's research administration office whether co-authorship needs to be registered internally.

Three service boundaries. We do not promise publication outcomes or a particular journal or impact factor. Our main support range is impact factor (IF) 1–5, with a capability ceiling of IF 1–10; targets above this range are discussed during assessment. Fees do not depend on publication outcomes. Payments are due on signing and before submission, independently of journal decisions; there are no post-acceptance revenue-sharing arrangements. Our services comprise methodological support, writing and revision. We do not ghostwrite. Our involvement in a paper is disclosed truthfully: where our staff meet the authorship criteria of the International Committee of Medical Journal Editors (ICMJE), they are listed as authors under our company's real affiliation; any other contribution is stated in the acknowledgements. Terms of service
In-scope revisions and quality responsibility

Includes statistical questions explicitly raised by reviewers in the journal decision letter concerning our analytical methods, up to 3 revisions.

Excludes rejection due to data limitations (insufficient sample size, missing key variables or incorrect eligibility definitions); requests beyond statistical methods (changing the research question or analysis population, or adding subanalyses); and additional data collection requested by reviewers.

If the journal decision letter explicitly identifies a methodological error in the statistical analysis as the reason for rejection, and it remains unresolved after 3 revisions or appeals by us, under Refund Policy Clause 2, fees paid for that stage are refunded in full. The original journal decision letter or reviewer comments must accompany the request as evidence. View the refund policy

06 Clinical Research

Pricing explained

Base scope from ¥12,800

The base quotation covers standard modelling with ≤30 variables and ≤2,000 participants. Additional work is priced in workload tiers, with surcharges itemised in the quotation before signing; no further charges are added after signing.

Publication outcomes and quality responsibility

Publication outcomes are not included. No organisation can promise acceptance by a particular journal. Our commitment is to the contractual statistical methodology quality provisions: if in-scope statistical questions from reviewers remain unresolved after 3 revisions or appeals, they are handled under Refund Policy Clause 2.

Package upgrades and fee credits

Yes. All fees paid for Collaboration starter are credited towards Full-service management; only the difference is payable. Please indicate your intention to upgrade before the project starts so that the design can accommodate the data interfaces needed later.

Invoices and payment options

Standard VAT invoices and special VAT invoices (增值税专用发票) are issued at agreed milestones after the collaboration agreement is signed. Collaboration starter and Full-service management support a single payment or two instalments (50% on signing + 50% before submission); Multicentre / RCT uses milestone payments.

Sample plans before signing

We can provide anonymised excerpts from design plans for similar studies. A complete plan tailored to your data is issued after the free assessment discussion.

Medical Writing pricing for industry

These prices do not apply. Medical writing and revision for pharmaceutical Medical Affairs teams begin with a Requirement confirmation form covering deliverable types and quantities, products and marketing status, material classification and intended use. An itemised quotation and agreed revision rounds follow.

See the service overview for the working processSee About us for the team and three-level quality control

Get started · Methodology assessment

Book a methodology assessment

Submit your research question, available data and intended outputs. Reply within 24 hours (business days first), with feasibility feedback, viable statistical approaches and a recommended package in our first response.

Request an assessmentFree assessment · Quote after assessment

Our involvement in a paper is disclosed truthfully: where our staff meet the ICMJE authorship criteria, they are listed as authors under our company's real affiliation; any other contribution is stated in the acknowledgements. Acceptance is decided by the journal editorial office and peer review. We do not promise publication outcomes.